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Nikeyia Ingram, 38, who was diagnosed with sickle cell disease (SCD) at just 6 months old, experiences pain nearly every day due to the red blood cell disorder. Most days, she’s able to treat the pain and manage her disease by controlling her stress, staying hydrated and keeping in touch with her medical team. Lately, Ingram has been finding that grief has been affecting her ability to manage her disease. Last year, she lost her 15-year-old, Demetrius Ingram, her only son, in a car accident. The heartache exacerbates her pain.

Think of the word “infertility,” and you might picture a couple without children struggling to get pregnant or stay pregnant. But there is another set of people — those who have successfully conceived and given birth to one or more children — who struggle with infertility, too. Called secondary infertility, the condition often carries an extra burden: Those affected by it might feel guilty over wanting another child; those close to them may be unsympathetic because they are already a parent; or frustrated because getting pregnant the first (or second) time was relatively easy.