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Bill Bunch’s favorite activities include golfing, tending to his yard, and playing catch with his grandson. Each one became more difficult and less enjoyable for the retiree during a six-year span in which a worsening back condition affected his hips, legs, and feet.

For neurologists working with patients with Alzheimer’s disease, the road to actual treatment options has been long and paved with setbacks. But that is changing for some patients.