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Twenty years after having her left hip replaced, Shelly Conley, 86, felt like something wasn’t quite right. She had a strange sensation deep in the hip joint that was shifting with every step, catching, and grinding in a way it hadn’t before.

Last fall, Pam Ludy, 65, took a trip with her sister to North Carolina. But Pam, who has osteoarthritis in both knees, had a hard time walking.