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Answers from the BJC Experts

Ask the BJC Expert allows you to get the answers you need about a variety of health, medicine and exercise issues to help you live a more healthy life.

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Can I take Tylenol PM with MethylPrednisolone 4mg dose pack?

There are no direct drug interactions between Tylenol PM (diphenhydramine,acetaminophen) and methylprednisolone (Medrol Dospak). Take the Tylenol product just before bedtime. Take the steroid as instructed on the package, until finished. Normally this is taken with food or milk to prevent stomach upset.

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