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Answers from the BJC Experts

Ask the BJC Expert allows you to get the answers you need about a variety of health, medicine and exercise issues to help you live a more healthy life.

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If I switch from Wellburtrin SR to Adderall (regular release), or vice-versa- how long should I wait for clearance before starting the other?

Switching from the regular release Adderall (mixed amphetamine salts) to Wellbutrin SR (bupropion sustained release) would require one day. From the other direction, bupropion SR to Adderall, I would suggest waiting 2 to 3 days. Serious side effects (examples: nervousness, irritability, sleeplessness, increased blood pressure, seizures and other side effects) from bupropion may get worse if you take these drugs together.

Also try to limit caffeine intake (examples: coffee, teas, colas, chocolate and some herbal supplements). Do not make any changes that are not prescribed by your physician.

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